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The Role of Monocarboxylate Transporters and Their Chaperone CD147 in Lactate Efflux Inhibition and the Anticancer Effects of Terminalia chebula in Neuroblastoma Cell Line N2-A

AIMS: In the presence of oxygen, most of the synthesized pyruvate during glycolysis in the cancer cell of solid tumors is released away from the mitochondria to form lactate (Warburg Effect). To maintain cell homeostasis, lactate is transported across the cell membrane by monocarboxylate transporter...

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Detalles Bibliográficos
Autores principales: Messeha, S. S., Zarmouh, N. O., Taka, E., Gendy, S. G., Shokry, G. R., Kolta, M. G., Soliman, K. F. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857771/
https://www.ncbi.nlm.nih.gov/pubmed/27158628
http://dx.doi.org/10.9734/EJMP/2016/23992