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KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes

Secretion of RNAs in extracellular vesicles is a newly recognized form of intercellular communication. A potential regulatory protein for microRNA (miRNA) secretion is the critical RNA-induced silencing complex (RISC) component Argonaute 2 (Ago2). Here, we use isogenic colon cancer cell lines to sho...

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Detalles Bibliográficos
Autores principales: McKenzie, Andrew J., Hoshino, Daisuke, Hong, Nan Hyung, Cha, Diana J., Franklin, Jeffrey L., Coffey, Robert J., Patton, James G., Weaver, Alissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857875/
https://www.ncbi.nlm.nih.gov/pubmed/27117408
http://dx.doi.org/10.1016/j.celrep.2016.03.085