Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

Whole genome analysis approaches are revealing recurrent cancer-associated somatic alterations in non-coding DNA regions. We combined somatic copy number analysis of 12 tumor types with tissue-specific epigenetic profiling to identify significant regions of focal amplification harboring super-enhanc...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyang, Choi, Peter S., Francis, Joshua M., Imielinski, Marcin, Watanabe, Hideo, Cherniack, Andrew D., Meyerson, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857881/
https://www.ncbi.nlm.nih.gov/pubmed/26656844
http://dx.doi.org/10.1038/ng.3470

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857881/
https://www.ncbi.nlm.nih.gov/pubmed/26656844
http://dx.doi.org/10.1038/ng.3470

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