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Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
Whole genome analysis approaches are revealing recurrent cancer-associated somatic alterations in non-coding DNA regions. We combined somatic copy number analysis of 12 tumor types with tissue-specific epigenetic profiling to identify significant regions of focal amplification harboring super-enhanc...
Autores principales: | Zhang, Xiaoyang, Choi, Peter S., Francis, Joshua M., Imielinski, Marcin, Watanabe, Hideo, Cherniack, Andrew D., Meyerson, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857881/ https://www.ncbi.nlm.nih.gov/pubmed/26656844 http://dx.doi.org/10.1038/ng.3470 |
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