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Identification of a Functional Risk Variant for Pemphigus Vulgaris in the ST18 Gene
Pemphigus vulgaris (PV) is a life-threatening autoimmune mucocutaneous blistering disease caused by disruption of intercellular adhesion due to auto-antibodies directed against epithelial components. Treatment is limited to immunosuppressive agents, which are associated with serious adverse effects....
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858139/ https://www.ncbi.nlm.nih.gov/pubmed/27148741 http://dx.doi.org/10.1371/journal.pgen.1006008 |