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Cyclic Equibiaxial Tensile Strain Alters Gene Expression of Chondrocytes via Histone Deacetylase 4 Shuttling

OBJECTIVES: This paper aims to investigate whether equibiaxial tensile strain alters chondrocyte gene expression via controlling subcellular localization of histone deacetylase 4 (HDAC4). MATERIALS AND METHODS: Murine chondrocytes transfected with GFP-HDAC4 were subjected to 3 h cyclic equibiaxial t...

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Detalles Bibliográficos
Autores principales: Chen, Chongwei, Wei, Xiaochun, Lv, Zhi, Sun, Xiaojuan, Wang, Shaowei, Zhang, Yang, Jiao, Qiang, Wang, Xiaohu, Li, Yongping, Wei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858146/
https://www.ncbi.nlm.nih.gov/pubmed/27149270
http://dx.doi.org/10.1371/journal.pone.0154951