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Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

The over-expression of human neuroglobin (NGB), a heme-protein preferentially expressed in the brain, displays anti-apoptotic effects against hypoxic/ischemic and oxidative stresses enhancing neuron survival. As hypoxic and oxidative stress injury frequently occurs in fast proliferating neoplastic t...

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Detalles Bibliográficos
Autores principales: Fiocchetti, Marco, Cipolletti, Manuela, Leone, Stefano, Naldini, Antonella, Carraro, Fabio, Giordano, Daniela, Verde, Cinzia, Ascenzi, Paolo, Marino, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858147/
https://www.ncbi.nlm.nih.gov/pubmed/27149623
http://dx.doi.org/10.1371/journal.pone.0154959