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Phosphorylation of Human Choline Kinase Beta by Protein Kinase A: Its Impact on Activity and Inhibition

Choline kinase beta (CKβ) is one of the CK isozymes involved in the biosynthesis of phosphatidylcholine. CKβ is important for normal mitochondrial function and muscle development as the lack of the ckβ gene in human and mice results in the development of muscular dystrophy. In contrast, CKα is impli...

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Detalles Bibliográficos
Autores principales: Chang, Ching Ching, Few, Ling Ling, Konrad, Manfred, See Too, Wei Cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858151/
https://www.ncbi.nlm.nih.gov/pubmed/27149373
http://dx.doi.org/10.1371/journal.pone.0154702