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Nucleotide-Specific Contrast for DNA Sequencing by Electron Spectroscopy
DNA sequencing by imaging in an electron microscope is an approach that holds promise to deliver long reads with low error rates and without the need for amplification. Earlier work using transmission electron microscopes, which use high electron energies on the order of 100 keV, has shown that low...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858156/ https://www.ncbi.nlm.nih.gov/pubmed/27149617 http://dx.doi.org/10.1371/journal.pone.0154707 |