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Exploiting Genetic Interference for Antiviral Therapy

Rapidly evolving viruses are a major threat to human health. Such viruses are often highly pathogenic (e.g., influenza virus, HIV, Ebola virus) and routinely circumvent therapeutic intervention through mutational escape. Error-prone genome replication generates heterogeneous viral populations that r...

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Detalles Bibliográficos
Autores principales: Tanner, Elizabeth J., Kirkegaard, Karla A., Weinberger, Leor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858160/
https://www.ncbi.nlm.nih.gov/pubmed/27149616
http://dx.doi.org/10.1371/journal.pgen.1005986