Cargando…

A Conserved DNA Repeat Promotes Selection of a Diverse Repertoire of Trypanosoma brucei Surface Antigens from the Genomic Archive

African trypanosomes are mammalian pathogens that must regularly change their protein coat to survive in the host bloodstream. Chronic trypanosome infections are potentiated by their ability to access a deep genomic repertoire of Variant Surface Glycoprotein (VSG) genes and switch from the expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Hovel-Miner, Galadriel, Mugnier, Monica R., Goldwater, Benjamin, Cross, George A. M., Papavasiliou, F. Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858185/
https://www.ncbi.nlm.nih.gov/pubmed/27149665
http://dx.doi.org/10.1371/journal.pgen.1005994