Alendronate Sodium as Enteric Coated Solid Lipid Nanoparticles; Preparation, Optimization, and In Vivo Evaluation to Enhance Its Oral Bioavailability

Treatment of osteoporosis with alendronate sodium has several challenges. The first challenge is the low bioavailability. The second main challenge is side effects, which include oesophageal ulceration. The aim of this research was to reformulate alendronate sodium as enteric coated solid lipid nano...

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Detalles Bibliográficos
Autor principal: Hosny, Khaled Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858199/
https://www.ncbi.nlm.nih.gov/pubmed/27148747
http://dx.doi.org/10.1371/journal.pone.0154926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858199/
https://www.ncbi.nlm.nih.gov/pubmed/27148747
http://dx.doi.org/10.1371/journal.pone.0154926

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