UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts

During transcription, most eukaryotic genes generate multiple alternative cleavage and polyadenylation (APA) sites, leading to the production of transcript isoforms with variable lengths in the 3’ untranslated region (3’UTR). In contrast to somatic cells, male germ cells, especially pachytene sperma...

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Detalles Bibliográficos
Autores principales: Bao, Jianqiang, Vitting-Seerup, Kristoffer, Waage, Johannes, Tang, Chong, Ge, Ying, Porse, Bo T., Yan, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858225/
https://www.ncbi.nlm.nih.gov/pubmed/27149259
http://dx.doi.org/10.1371/journal.pgen.1005863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858225/
https://www.ncbi.nlm.nih.gov/pubmed/27149259
http://dx.doi.org/10.1371/journal.pgen.1005863

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