RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases

The human genome contains six genes coding for proteins validated in vitro as specific activators of the small GTPases “Ras-related protein Ral-A” and “Ras-related protein Ral-B”, generically named Ral-guanine nucleotide exchange factors (RalGEF). Ral proteins are important contributors to Ras oncog...

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Detalles Bibliográficos
Autores principales: O. Santos, Adriana, Parrini, Maria Carla, Camonis, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858283/
https://www.ncbi.nlm.nih.gov/pubmed/27149377
http://dx.doi.org/10.1371/journal.pone.0154840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858283/
https://www.ncbi.nlm.nih.gov/pubmed/27149377
http://dx.doi.org/10.1371/journal.pone.0154840

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