Estradiol Enhances CD4(+) T-Cell Anti-Viral Immunity by Priming Vaginal DCs to Induce T(h)17 Responses via an IL-1-Dependent Pathway

Clinical and experimental studies have shown that estradiol (E2) confers protection against HIV and other sexually transmitted infections. Here, we investigated the underlying mechanism. Better protection in E2-treated mice, immunized against genital HSV-2, coincided with earlier recruitment and hig...

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Detalles Bibliográficos
Autores principales: Anipindi, Varun C., Bagri, Puja, Roth, Kristy, Dizzell, Sara E., Nguyen, Philip V., Shaler, Christopher R., Chu, Derek K., Jiménez-Saiz, Rodrigo, Liang, Hong, Swift, Stephanie, Nazli, Aisha, Kafka, Jessica K., Bramson, Jonathan, Xing, Zhou, Jordana, Manel, Wan, Yonghong, Snider, Denis P., Stampfli, Martin R., Kaushic, Charu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858291/
https://www.ncbi.nlm.nih.gov/pubmed/27148737
http://dx.doi.org/10.1371/journal.ppat.1005589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858291/
https://www.ncbi.nlm.nih.gov/pubmed/27148737
http://dx.doi.org/10.1371/journal.ppat.1005589

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