Developmental Effects of the ToxCast™ Phase I and Phase II Chemicals in Caenorhabditis elegans and Corresponding Responses in Zebrafish, Rats, and Rabbits

BACKGROUND: Modern toxicology is shifting from an observational to a mechanistic science. As part of this shift, high-throughput toxicity assays are being developed using alternative, nonmammalian species to prioritize chemicals and develop prediction models of human toxicity. METHODS: The nematode...

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Detalles Bibliográficos
Autores principales: Boyd, Windy A., Smith, Marjolein V., Co, Caroll A., Pirone, Jason R., Rice, Julie R., Shockley, Keith R., Freedman, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858399/
https://www.ncbi.nlm.nih.gov/pubmed/26496690
http://dx.doi.org/10.1289/ehp.1409645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858399/
https://www.ncbi.nlm.nih.gov/pubmed/26496690
http://dx.doi.org/10.1289/ehp.1409645

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