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Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood

BACKGROUND: Lead exposure during early development causes neurodevelopmental disorders by unknown mechanisms. Epidemiologic studies have focused recently on determining associations between lead exposure and global DNA methylation; however, such approaches preclude the identification of loci that ma...

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Detalles Bibliográficos
Autores principales: Li, Yue, Xie, Changchun, Murphy, Susan K., Skaar, David, Nye, Monica, Vidal, Adriana C., Cecil, Kim M., Dietrich, Kim N., Puga, Alvaro, Jirtle, Randy L., Hoyo, Cathrine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858407/
https://www.ncbi.nlm.nih.gov/pubmed/26115033
http://dx.doi.org/10.1289/ehp.1408577