Characterization of procoagulant extracellular vesicles and platelet membrane disintegration in DMSO-cryopreserved platelets

BACKGROUND: Freezing is promising for extended platelet (PLT) storage for transfusion. 6% DMSO cryopreserved PLTs (CPPs) are currently in clinical development. CPPs contain significant amount of platelet membrane vesicles (PMVs). PLT-membrane changes and PMV release in CPP are poorly understood, and...

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Detalles Bibliográficos
Autores principales: Tegegn, Tseday Z., De Paoli, Silvia H., Orecna, Martina, Elhelu, Oumsalama K., Woodle, Samuel A., Tarandovskiy, Ivan D., Ovanesov, Mikhail V., Simak, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2016
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858502/
https://www.ncbi.nlm.nih.gov/pubmed/27151397
http://dx.doi.org/10.3402/jev.v5.30422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858502/
https://www.ncbi.nlm.nih.gov/pubmed/27151397
http://dx.doi.org/10.3402/jev.v5.30422

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