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Potentiation of Gamma Aminobutyric Acid Receptors (GABA(A)R) by Ethanol: How Are Inhibitory Receptors Affected?

In recent years there has been an increase in the understanding of ethanol actions on the type A γ-aminobutyric acid chloride channel (GABA(A)R), a member of the pentameric ligand gated ion channels (pLGICs). However, the mechanism by which ethanol potentiates the complex is still not fully understo...

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Detalles Bibliográficos
Autores principales: Förstera, Benjamin, Castro, Patricio A., Moraga-Cid, Gustavo, Aguayo, Luis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858537/
https://www.ncbi.nlm.nih.gov/pubmed/27199667
http://dx.doi.org/10.3389/fncel.2016.00114