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eEF1A1 binds and enriches protoporphyrin IX in cancer cells in 5-aminolevulinic acid based photodynamic therapy
Photodynamic therapy (PDT) with protoporphyrin IX (PpIX), which is endogenously derived from 5-aminolevulinic acid (5-ALA) or its derivatives, is a promising modality for the treatment of both pre-malignant and malignant lesions. However, the mechanisms of how ALA-induced PpIX selectively accumulate...
Autores principales: | Fan, Zhichao, Cui, Xiaojun, Wei, Dan, Liu, Wei, Li, Buhong, He, Hao, Ye, Huamao, Zhu, Naishuo, Wei, Xunbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858656/ https://www.ncbi.nlm.nih.gov/pubmed/27150264 http://dx.doi.org/10.1038/srep25353 |
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