The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms

IL-18 is a member of the IL-1 family involved in innate immunity and inflammation. Deregulated levels of IL-18 are involved in the pathogenesis of multiple disorders including inflammatory and metabolic diseases, yet relatively little is known regarding its regulation. Liver X receptors or LXRs are...

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Detalles Bibliográficos
Autores principales: Pourcet, Benoit, Gage, Matthew C., León, Theresa E., Waddington, Kirsty E., Pello, Oscar M., Steffensen, Knut R., Castrillo, Antonio, Valledor, Annabel F., Pineda-Torra, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858669/
https://www.ncbi.nlm.nih.gov/pubmed/27149934
http://dx.doi.org/10.1038/srep25481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858669/
https://www.ncbi.nlm.nih.gov/pubmed/27149934
http://dx.doi.org/10.1038/srep25481

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