Measuring changes in substrate utilization in the myocardium in response to fasting using hyperpolarized [1-(13)C]butyrate and [1-(13)C]pyruvate

Cardiac dysfunction is often associated with a shift in substrate preference for ATP production. Hyperpolarized (HP) (13)C magnetic resonance spectroscopy (MRS) has the unique ability to detect real-time metabolic changes in vivo due to its high sensitivity and specificity. Here a protocol using HP...

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Detalles Bibliográficos
Autores principales: Bastiaansen, Jessica A. M., Merritt, Matthew E., Comment, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858671/
https://www.ncbi.nlm.nih.gov/pubmed/27150735
http://dx.doi.org/10.1038/srep25573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858671/
https://www.ncbi.nlm.nih.gov/pubmed/27150735
http://dx.doi.org/10.1038/srep25573

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