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Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles

We report that a combination of anti-HIV-1 drug efavirenz (EFV), anti-microbial-spermicidal curcumin (Cur) and lactoferrin nanoparticles (ECNPs) act as MPT formulation. These nanoparticles are of well dispersed spherical shape with 40–70 nm size, with encapsulation efficiency of 63 ± 1.9% of Cur &am...

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Detalles Bibliográficos
Autores principales: Lakshmi, Yeruva Samrajya, Kumar, Prashant, Kishore, Golla, Bhaskar, C, Kondapi, Anand K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858693/
https://www.ncbi.nlm.nih.gov/pubmed/27151598
http://dx.doi.org/10.1038/srep25479