Cargando…

Triple combination MPT vaginal microbicide using curcumin and efavirenz loaded lactoferrin nanoparticles

We report that a combination of anti-HIV-1 drug efavirenz (EFV), anti-microbial-spermicidal curcumin (Cur) and lactoferrin nanoparticles (ECNPs) act as MPT formulation. These nanoparticles are of well dispersed spherical shape with 40–70 nm size, with encapsulation efficiency of 63 ± 1.9% of Cur &am...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lakshmi, Yeruva Samrajya, Kumar, Prashant, Kishore, Golla, Bhaskar, C, Kondapi, Anand K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858693/ https://www.ncbi.nlm.nih.gov/pubmed/27151598 http://dx.doi.org/10.1038/srep25479

Ejemplares similares

Improved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in Rats
por: Kumar, Prashant, et al.
Publicado: (2015)

Curcumin-Loaded Apotransferrin Nanoparticles Provide Efficient Cellular Uptake and Effectively Inhibit HIV-1 Replication In Vitro
por: Gandapu, Upendhar, et al.
Publicado: (2011)

A Target-Specific Oral Formulation of Doxorubicin-Protein Nanoparticles: Efficacy and Safety in Hepatocellular Cancer
por: Golla, Kishore, et al.
Publicado: (2013)

Efficacy, Safety and Anticancer Activity of Protein Nanoparticle-Based Delivery of Doxorubicin through Intravenous Administration in Rats
por: Golla, Kishore, et al.
Publicado: (2012)

An Efficient Targeted Drug Delivery through Apotransferrin Loaded Nanoparticles
por: Krishna, Athuluri Divakar Sai, et al.
Publicado: (2009)

Vaginal rings for delivery of HIV microbicides
por: Malcolm, R Karl, et al.
Publicado: (2012)

Overcoming blood brain barrier with a dual purpose Temozolomide loaded Lactoferrin nanoparticles for combating glioma (SERP-17-12433)
por: Kumari, Sonali, et al.
Publicado: (2017)

The Development of Vaginal Microbicides for the Prevention of HIV Transmission
por: Weber, Jonathan, et al.
Publicado: (2005)

Vaginal deployment and tenofovir delivery by microbicide gels
por: Gao, Y., et al.
Publicado: (2015)

Carboplatin- and Etoposide-Loaded Lactoferrin Protein Nanoparticles for Targeting Cancer Stem Cells in Retinoblastoma In Vitro
por: Narayana, Revu V. L., et al.
Publicado: (2021)

Potential Use of Antimicrobial Peptides as Vaginal Spermicides/Microbicides
por: Tanphaichitr, Nongnuj, et al.
Publicado: (2016)

Microbicides Development Programme: Engaging the community in the standard of care debate in a vaginal microbicide trial in Mwanza, Tanzania
por: Vallely, Andrew, et al.
Publicado: (2009)

Efficacy dilution in randomized placebo-controlled vaginal microbicide trials
por: Mâsse, Benoît R, et al.
Publicado: (2009)

Twice-Daily Application of HIV Microbicides Alters the Vaginal Microbiota
por: Ravel, Jacques, et al.
Publicado: (2012)

Do vaginal microbicides reduce the risk of HIV acquisition in women?
por: Obiero, Jael Apondi, et al.
Publicado: (2022)

Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission
por: Cone, Richard A, et al.
Publicado: (2006)

Analysis of Vaginal Microbicide Film Hydration Kinetics by Quantitative Imaging Refractometry
por: Rinehart, Matthew, et al.
Publicado: (2014)

Pharmaceutical Vehicles for Vaginal and Rectal Administration of Anti-HIV Microbicide Nanosystems
por: Mesquita, Letícia, et al.
Publicado: (2019)

Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
por: Rahman, Mohammad Arif, et al.
Publicado: (2023)

Microbicides Development Programme: design of a phase III trial to measure the efficacy of the vaginal microbicide PRO 2000/5 for HIV prevention
por: Nunn, Andrew, et al.
Publicado: (2009)

Development of pre-clinical and clinical models to predict the efficacy and safety of vaginal microbicides
por: Herold, Betsy C
Publicado: (2006)

Increasing the Effectiveness of Vaginal Microbicides: A Biophysical Framework to Rethink Behavioral Acceptability
por: Verguet, Stéphane, et al.
Publicado: (2010)

Vaginal pH and Microbicidal Lactic Acid When Lactobacilli Dominate the Microbiota
por: O’Hanlon, Deirdre E., et al.
Publicado: (2013)

The Implications of Post-coital Intravaginal Cleansing for the Introduction of Vaginal Microbicides in South Africa
por: Gafos, Mitzy, et al.
Publicado: (2013)

G2-S16 dendrimer microbicide does not interfere with the vaginal immune system
por: Martín-Moreno, Alba, et al.
Publicado: (2019)

Characterization of proteolytic degradation products of vaginally administered bovine lactoferrin
por: Hopp, Thomas P., et al.
Publicado: (2022)

Cervicovaginal fluid and semen block the microbicidal activity of hydrogen peroxide produced by vaginal lactobacilli
por: O'Hanlon, Deirdre E, et al.
Publicado: (2010)

Quantitative assessment of microbicide-induced injury in the ovine vaginal epithelium using confocal microendoscopy
por: Vargas, Gracie, et al.
Publicado: (2012)

Novel Vaginal Microflora Colonization Model Providing New Insight into Microbicide Mechanism of Action
por: Fichorova, Raina N., et al.
Publicado: (2011)

Homeostatic properties of Lactobacillus jensenii engineered as a live vaginal anti-HIV microbicide
por: Yamamoto, Hidemi S, et al.
Publicado: (2013)

Clinical use of vaginal or rectally applied microbicides in patients suffering from HIV/AIDS
por: Gupta, Satish Kumar, et al.
Publicado: (2013)

An assessment of the likely acceptability of vaginal microbicides for HIV prevention among women in rural Ghana
por: Abdulai, Martha A, et al.
Publicado: (2012)

Glycerol Monolaurate Microbicide Protection against Repeat High-Dose SIV Vaginal Challenge
por: Haase, Ashley T., et al.
Publicado: (2015)

Publisher Correction: Vaccine plus microbicide effective in preventing vaginal SIV transmission in macaques
por: Rahman, Mohammad Arif, et al.
Publicado: (2023)

Effects of Curcumin and Lactoferrin to Inhibit the Growth and Migration of Prostatic Cancer Cells
por: Costantini, Erica, et al.
Publicado: (2022)

Vaginal lactobacilli profile in pregnant women with normal & abnormal vaginal flora
por: Yeruva, Thirupathaiah, et al.
Publicado: (2017)

Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching
por: Mishra, Arun K, et al.
Publicado: (2011)

Unexpected synergistic HIV neutralization by a triple microbicide produced in rice endosperm
por: Vamvaka, Evangelia, et al.
Publicado: (2018)

Warding Off Recurrent Yeast and Bacterial Vaginal Infections: Lactoferrin and Lactobacilli
por: Superti, Fabiana, et al.
Publicado: (2020)

Acceptability of Carraguard Vaginal Microbicide Gel among HIV-Infected Women in Chiang Rai, Thailand
por: Whitehead, Sara J., et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_tdp8apv2ljup9psn30ekvsec9h