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Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway

TNF-receptor associated factor (TRAF) proteins are key adaptor molecules containing E3 ubiquitin ligase activity that play a critical role in immune cell signaling. TRAF1 is a unique family of TRAF lacking the N-terminal RING finger domain. TRAF1 is an important scaffold protein that participates in...

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Detalles Bibliográficos
Autores principales: Kim, Chang Min, Choi, Jae Young, Bhat, Eijaz Ahmed, Jeong, Jae-Hee, Son, Young-Jin, Kim, Sunghwan, Park, Hyun Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858697/
https://www.ncbi.nlm.nih.gov/pubmed/27151821
http://dx.doi.org/10.1038/srep25526