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Evolved resistance to colistin and its loss due to genetic reversion in Pseudomonas aeruginosa

The increased reliance on colistin for treating multidrug-resistant Gram-negative bacterial infections has resulted in the emergence of colistin-resistant Pseudomonas aeruginosa. We attempted to identify genetic contributors to colistin resistance in vitro evolved isogenic colistin-resistant and -su...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Young, Park, Young Kyoung, Chung, Eun Seon, Na, In Young, Ko, Kwan Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858706/
https://www.ncbi.nlm.nih.gov/pubmed/27150578
http://dx.doi.org/10.1038/srep25543