Bifunctional CYP81AA proteins catalyse identical hydroxylations but alternative regioselective phenol couplings in plant xanthone biosynthesis

Xanthones are natural products present in plants and microorganisms. In plants, their biosynthesis starts with regioselective cyclization of 2,3′,4,6-tetrahydroxybenzophenone to either 1,3,5- or 1,3,7-trihydroxyxanthones, catalysed by cytochrome P450 (CYP) enzymes. Here we isolate and express CYP81A...

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Detalles Bibliográficos
Autores principales: El-Awaad, Islam, Bocola, Marco, Beuerle, Till, Liu, Benye, Beerhues, Ludger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858744/
https://www.ncbi.nlm.nih.gov/pubmed/27145837
http://dx.doi.org/10.1038/ncomms11472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858744/
https://www.ncbi.nlm.nih.gov/pubmed/27145837
http://dx.doi.org/10.1038/ncomms11472

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