Differential Phosphorylation Provides a Switch to Control How α-Arrestin Rod1 Down-regulates Mating Pheromone Response in Saccharomyces cerevisiae

G-protein-coupled receptors (GPCRs) are integral membrane proteins that initiate stimulus-dependent activation of cognate heterotrimeric G-proteins, triggering ensuing downstream cellular responses. Tight regulation of GPCR-evoked pathways is required because prolonged stimulation can be detrimental...

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Detalles Bibliográficos
Autores principales: Alvaro, Christopher G., Aindow, Ann, Thorner, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2016
Materias:
Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858781/
https://www.ncbi.nlm.nih.gov/pubmed/26920760
http://dx.doi.org/10.1534/genetics.115.186122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858781/
https://www.ncbi.nlm.nih.gov/pubmed/26920760
http://dx.doi.org/10.1534/genetics.115.186122

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