Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development

BACKGROUND: Recent advances in sequencing technologies enable the large-scale identification of genes that are affected by various genetic alterations in cancer. However, understanding tumor development requires insights into how these changes cause altered protein function and impaired network regu...

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Detalles Bibliográficos
Autores principales: Mészáros, Bálint, Zeke, András, Reményi, Attila, Simon, István, Dosztányi, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858844/
https://www.ncbi.nlm.nih.gov/pubmed/27150584
http://dx.doi.org/10.1186/s13062-016-0125-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858844/
https://www.ncbi.nlm.nih.gov/pubmed/27150584
http://dx.doi.org/10.1186/s13062-016-0125-6

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