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Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development
BACKGROUND: Recent advances in sequencing technologies enable the large-scale identification of genes that are affected by various genetic alterations in cancer. However, understanding tumor development requires insights into how these changes cause altered protein function and impaired network regu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858844/ https://www.ncbi.nlm.nih.gov/pubmed/27150584 http://dx.doi.org/10.1186/s13062-016-0125-6 |