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Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage

BACKGROUND: Marrow mesenchymal stem cells (MSCs) can differentiate into specific phenotypes, including chondrocytes, and have been widely used for cartilage tissue engineering. However, cartilage grafts from MSCs exhibit phenotypic alternations after implantation, including matrix calcification and...

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Detalles Bibliográficos
Autores principales: Chen, Zhuoyue, Wei, Jing, Zhu, Jun, Liu, Wei, Cui, Jihong, Li, Hongmin, Chen, Fulin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858869/
https://www.ncbi.nlm.nih.gov/pubmed/27150539
http://dx.doi.org/10.1186/s13287-016-0328-x