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Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage
BACKGROUND: Marrow mesenchymal stem cells (MSCs) can differentiate into specific phenotypes, including chondrocytes, and have been widely used for cartilage tissue engineering. However, cartilage grafts from MSCs exhibit phenotypic alternations after implantation, including matrix calcification and...
Autores principales: | Chen, Zhuoyue, Wei, Jing, Zhu, Jun, Liu, Wei, Cui, Jihong, Li, Hongmin, Chen, Fulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858869/ https://www.ncbi.nlm.nih.gov/pubmed/27150539 http://dx.doi.org/10.1186/s13287-016-0328-x |
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