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In silico lineage tracing through single cell transcriptomics identifies a neural stem cell population in planarians
BACKGROUND: The planarian Schmidtea mediterranea is a master regenerator with a large adult stem cell compartment. The lack of transgenic labeling techniques in this animal has hindered the study of lineage progression and has made understanding the mechanisms of tissue regeneration a challenge. How...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858873/ https://www.ncbi.nlm.nih.gov/pubmed/27150006 http://dx.doi.org/10.1186/s13059-016-0937-9 |