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Histamine 1 receptor-G(βγ)-cAMP/PKA-CFTR pathway mediates the histamine-induced resetting of the suprachiasmatic circadian clock
BACKGROUND: Recent evidence indicates that histamine, acting on histamine 1 receptor (H1R), resets the circadian clock in the mouse suprachiasmatic nucleus (SCN) by increasing intracellular Ca(2+) concentration ([Ca(2+)](i)) through the activation of Ca(V)1.3 L-type Ca(2+) channels and Ca(2+)-induce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858891/ https://www.ncbi.nlm.nih.gov/pubmed/27153809 http://dx.doi.org/10.1186/s13041-016-0227-1 |