Improvements to the HITS-CLIP protocol eliminate widespread mispriming artifacts

BACKGROUND:  High-throughput sequencing of RNA isolated by crosslinking immunoprecipitation (HITS-CLIP) allows for high resolution, genome-wide mapping of RNA-binding proteins. This methodology is frequently used to validate predicted targets of microRNA binding, as well as direct targets of other R...

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Detalles Bibliográficos
Autores principales: Gillen, Austin E., Yamamoto, Tomomi M., Kline, Enos, Hesselberth, Jay R., Kabos, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858895/
https://www.ncbi.nlm.nih.gov/pubmed/27150721
http://dx.doi.org/10.1186/s12864-016-2675-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858895/
https://www.ncbi.nlm.nih.gov/pubmed/27150721
http://dx.doi.org/10.1186/s12864-016-2675-5

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