Improving the N-terminal diversity of sansanmycin through mutasynthesis

BACKGROUND: Sansanmycins are uridyl peptide antibiotics (UPAs), which are inhibitors of translocase I (MraY) and block the bacterial cell wall biosynthesis. They have good antibacterial activity against Pseudomonas aeruginosa and Mycobacterium tuberculosis strains. The biosynthetic gene cluster of s...

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Detalles Bibliográficos
Autores principales: Shi, Yuanyuan, Jiang, Zhibo, Lei, Xuan, Zhang, Ningning, Cai, Qiang, Li, Qinglian, Wang, Lifei, Si, Shuyi, Xie, Yunying, Hong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858918/
https://www.ncbi.nlm.nih.gov/pubmed/27154005
http://dx.doi.org/10.1186/s12934-016-0471-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858918/
https://www.ncbi.nlm.nih.gov/pubmed/27154005
http://dx.doi.org/10.1186/s12934-016-0471-1

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