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Cysteamine broadly improves the anti-plasmodial activity of artemisinins against murine blood stage and cerebral malaria

BACKGROUND: The potential emergence and spread of resistance to artemisinins in the Plasmodium falciparum malaria parasite constitutes a major global health threat. Hence, improving the efficacy of artemisinins and of artemisinin-based combination therapy (ACT) represents a major short-term goal in...

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Detalles Bibliográficos
Autores principales: Moradin, Neda, Torre, Sabrina, Gauthier, Susan, Tam, Mifong, Hawari, Jalal, Vandercruyssen, Kirsten, De Spiegeleer, Bart, Fortin, Anny, Stevenson, Mary M., Gros, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858922/
https://www.ncbi.nlm.nih.gov/pubmed/27150250
http://dx.doi.org/10.1186/s12936-016-1317-3