Parkin Regulates the Activity of Pyruvate Kinase M2

Parkin, a ubiquitin E3 ligase, is mutated in most cases of autosomal recessive early onset Parkinson disease. It was discovered that Parkin is also mutated in glioblastoma and other human malignancies and that it inhibits tumor cell growth. Here, we identified pyruvate kinase M2 (PKM2) as a unique s...

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Detalles Bibliográficos
Autores principales: Liu, Kun, Li, Fanzhou, Han, Haichao, Chen, Yue, Mao, Zebin, Luo, Jianyuan, Zhao, Yingming, Zheng, Bin, Gu, Wei, Zhao, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Signal Transduction
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858978/
https://www.ncbi.nlm.nih.gov/pubmed/26975375
http://dx.doi.org/10.1074/jbc.M115.703066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858978/
https://www.ncbi.nlm.nih.gov/pubmed/26975375
http://dx.doi.org/10.1074/jbc.M115.703066

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