Inhibition of Heat Shock Protein 90 Prevents HIV Rebound

HIV evades eradication because transcriptionally dormant proviral genomes persist in long-lived reservoirs of resting CD4(+) T cells and myeloid cells, which are the source of viral rebound after cessation of antiretroviral therapy. Dormant HIV genomes readily produce infectious virus upon cellular...

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Detalles Bibliográficos
Autores principales: Joshi, Pheroze, Maidji, Ekaterina, Stoddart, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858980/
https://www.ncbi.nlm.nih.gov/pubmed/26957545
http://dx.doi.org/10.1074/jbc.M116.717538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858980/
https://www.ncbi.nlm.nih.gov/pubmed/26957545
http://dx.doi.org/10.1074/jbc.M116.717538

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