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Inhibition of Heat Shock Protein 90 Prevents HIV Rebound

HIV evades eradication because transcriptionally dormant proviral genomes persist in long-lived reservoirs of resting CD4(+) T cells and myeloid cells, which are the source of viral rebound after cessation of antiretroviral therapy. Dormant HIV genomes readily produce infectious virus upon cellular...

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Detalles Bibliográficos
Autores principales:	Joshi, Pheroze, Maidji, Ekaterina, Stoddart, Cheryl A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Molecular Bases of Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858980/ https://www.ncbi.nlm.nih.gov/pubmed/26957545 http://dx.doi.org/10.1074/jbc.M116.717538

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