Cargando…

A novel live cell assay to measure diacylglycerol lipase α activity

Diacylglycerol lipase α (DAGLα) hydrolyses DAG to generate the principal endocannabinoid (eCB) 2-arachidonoylglycerol (2-AG) in the central nervous system. DAGLα dependent cannabinoid (CB) signalling has been implicated in numerous processes including axonal growth and guidance, adult neurogenesis a...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Praveen K., Markwick, Rachel, Howell, Fiona V., Williams, Gareth, Doherty, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859088/
https://www.ncbi.nlm.nih.gov/pubmed/27013337
http://dx.doi.org/10.1042/BSR20160073