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Evaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model

Purpose: 2-hydroxy estradiol (2-OHE2) is a catechol derivative of 17β -Estradiol (E2) and it is synthesized from E2 catalyzed by cytochrome P4501A1. Previous studies reported that 2-OHE2 is a physiologic antioxidant in lipoproteins, liver microsomes, and the brain. Catechol derivatives show an anti-...

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Detalles Bibliográficos
Autores principales: Higuchi, Akihiro, Oonishi, Erina, Kawakita, Tetsuya, Tsubota, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859160/
https://www.ncbi.nlm.nih.gov/pubmed/27186071