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Prasugrel, a Platelet P2Y(12) Receptor Antagonist, Improves Abnormal Gait in a Novel Murine Model of Thrombotic Hindlimb Ischemia

BACKGROUND: The efficacy of P2Y(12) inhibition for the prevention of cardiovascular events in patients with peripheral arterial disease (PAD) has been established. However, the therapeutic effects on ischemic limb complications are less clear. Accordingly, we aimed to develop a novel murine model of...

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Detalles Bibliográficos
Autores principales: Ohno, Kousaku, Tomizawa, Atsuyuki, Mizuno, Makoto, Jakubowski, Joseph A., Sugidachi, Atsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859280/
https://www.ncbi.nlm.nih.gov/pubmed/27053057
http://dx.doi.org/10.1161/JAHA.115.002889