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Effects of Restoration of Blood Flow on the Development of Aortic Atherosclerosis in ApoE(−/−) Mice With Unilateral Renal Artery Stenosis

BACKGROUND: Chronic unilateral renal artery stenosis (RAS) causes accelerated atherosclerosis in apolipoprotein E–deficient (ApoE(−/−)) mice, but effects of restoration of renal blood flow on aortic atherosclerosis are unknown. METHODS AND RESULTS: Male ApoE(−/−) mice underwent sham surgery (n=16) o...

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Detalles Bibliográficos
Autores principales: Pathak, Alokkumar S., Huang, Jianhua, Rojas, Mauricio, Bazemore, Taylor C., Zhou, Ruihai, Stouffer, George A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859283/
https://www.ncbi.nlm.nih.gov/pubmed/27039929
http://dx.doi.org/10.1161/JAHA.115.002953