Integrated Regional Cardiac Hemodynamic Imaging and RNA Sequencing Reveal Corresponding Heterogeneity of Ventricular Wall Shear Stress and Endocardial Transcriptome

BACKGROUND: Unlike arteries, in which regionally distinct hemodynamics are associated with phenotypic heterogeneity, the relationships between endocardial endothelial cell phenotype and intraventricular flow remain largely unexplored. We investigated regional differences in left ventricular wall she...

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Detalles Bibliográficos
Autores principales: McCormick, Margaret E., Manduchi, Elisabetta, Witschey, Walter R. T., Gorman, Robert C., Gorman, Joseph H., Jiang, Yi‐Zhou, Stoeckert, Christian J., Barker, Alex J., Markl, Michael, Davies, Peter F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859290/
https://www.ncbi.nlm.nih.gov/pubmed/27091183
http://dx.doi.org/10.1161/JAHA.115.003170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859290/
https://www.ncbi.nlm.nih.gov/pubmed/27091183
http://dx.doi.org/10.1161/JAHA.115.003170

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