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Integrated Regional Cardiac Hemodynamic Imaging and RNA Sequencing Reveal Corresponding Heterogeneity of Ventricular Wall Shear Stress and Endocardial Transcriptome
BACKGROUND: Unlike arteries, in which regionally distinct hemodynamics are associated with phenotypic heterogeneity, the relationships between endocardial endothelial cell phenotype and intraventricular flow remain largely unexplored. We investigated regional differences in left ventricular wall she...
Autores principales: | McCormick, Margaret E., Manduchi, Elisabetta, Witschey, Walter R. T., Gorman, Robert C., Gorman, Joseph H., Jiang, Yi‐Zhou, Stoeckert, Christian J., Barker, Alex J., Markl, Michael, Davies, Peter F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859290/ https://www.ncbi.nlm.nih.gov/pubmed/27091183 http://dx.doi.org/10.1161/JAHA.115.003170 |
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