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Rnd3 as a Novel Target to Ameliorate Microvascular Leakage

BACKGROUND: Microvascular leakage of plasma proteins is a hallmark of inflammation that leads to tissue dysfunction. There are no current therapeutic strategies to reduce microvascular permeability. The purpose of this study was to identify the role of Rnd3, an atypical Rho family GTPase, in the con...

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Detalles Bibliográficos
Autores principales: Breslin, Jerome W., Daines, Dayle A., Doggett, Travis M., Kurtz, Kristine H., Souza‐Smith, Flavia M., Zhang, Xun E., Wu, Mack H., Yuan, Sarah Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859298/
https://www.ncbi.nlm.nih.gov/pubmed/27048969
http://dx.doi.org/10.1161/JAHA.116.003336