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Design and conduct of the activated protein C and corticosteroids for human septic shock (APROCCHSS) trial

BACKGROUND: We aimed at assessing the benefit-to-risk ratio of activated protein C (drotrecogin-alfa activated, DAA) and corticosteroids, given alone or in combination, in patients with septic shock. METHODS: We implemented an investigator-led, publicly funded, multicenter, randomized according to a...

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Detalles Bibliográficos
Autores principales: Annane, Djillali, Buisson, Christian Brun, Cariou, Alain, Martin, Claude, Misset, Benoit, Renault, Alain, Lehmann, Blandine, Millul, Valérie, Maxime, Virginie, Bellissant, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859323/
https://www.ncbi.nlm.nih.gov/pubmed/27154719
http://dx.doi.org/10.1186/s13613-016-0147-3