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Overexpression of Nitric Oxide Synthase Restores Circulating Angiogenic Cell Function in Patients With Coronary Artery Disease: Implications for Autologous Cell Therapy for Myocardial Infarction

BACKGROUND: Circulating angiogenic cells (CACs) are peripheral blood cells whose functional capacity inversely correlates with cardiovascular risk and that have therapeutic benefits in animal models of cardiovascular disease. However, donor age and disease state influence the efficacy of autologous...

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Detalles Bibliográficos
Autores principales: Chen, Qiumei, Varga, Monika, Wang, Xiaoyin, Haddad, Daniel J., An, Songtao, Medzikovic, Lejla, Derakhshandeh, Ronak, Kostyushev, Dmitry S., Zhang, Yan, Clifford, Brian T., Luu, Emmy, Danforth, Olivia M., Rafikov, Ruslan, Gong, Wenhui, Black, Stephen M., Suchkov, Sergey V., Fineman, Jeffrey R., Heiss, Christian, Aschbacher, Kirstin, Yeghiazarians, Yerem, Springer, Matthew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859354/
https://www.ncbi.nlm.nih.gov/pubmed/26738788
http://dx.doi.org/10.1161/JAHA.115.002257