Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease

BACKGROUND: Mitochondrial reactive oxygen species (ROS) are associated with metabolic heart disease (MHD). However, the mechanism by which ROS cause MHD is unknown. We tested the hypothesis that mitochondrial ROS are a key mediator of MHD. METHODS AND RESULTS: Mice fed a high‐fat high‐sucrose (HFHS)...

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Detalles Bibliográficos
Autores principales: Sverdlov, Aaron L., Elezaby, Aly, Qin, Fuzhong, Behring, Jessica B., Luptak, Ivan, Calamaras, Timothy D., Siwik, Deborah A., Miller, Edward J., Liesa, Marc, Shirihai, Orian S., Pimentel, David R., Cohen, Richard A., Bachschmid, Markus M., Colucci, Wilson S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859372/
https://www.ncbi.nlm.nih.gov/pubmed/26755553
http://dx.doi.org/10.1161/JAHA.115.002555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859372/
https://www.ncbi.nlm.nih.gov/pubmed/26755553
http://dx.doi.org/10.1161/JAHA.115.002555

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